Most of us assume reality is made up of physical matter. And contemporary science has built ever-larger machines to identify the ultimate particles from which everything else is made. Instead of getting closer to the most elementary material however, the particle zoo has got ever more complex and seemingly less like material stuff at all. Is there a danger that the very idea of an ultimate foundation to reality is a profound mistake? Some have proposed that instead of material the ultimate foundation is to be found in consciousness, information, or even some claim mathematics. But such proposals are no closer to identifying ultimate elements of reality than particle physicists.  

Should we give up the attempt to uncover an ultimate foundation to the universe? Is our inability to find an ultimate foundation a limitation of language, or of our capacity to make sense of the world, or is it to do with the nature of reality itself? Or is it just possible that if we hold in there, one day we will crack the ultimate puzzle?