Dawkins' Selfish Gene has been hugely influential, both within evolutionary biology and in the wider public sphere. It's a beautiful, simple story: genes and not organisms drive evolutionary change. But critics argue the story is simplistic. The effect of a gene is not always the same and is dependent on its host and the cell environment. Denis Noble, a pioneer of systems biology, goes further arguing that the organism and not genes are in charge.  
Is it time to move on and acknowledge that Dawkins' theory is not the whole story? Might his theory be making a fundamental mistake in reducing humans to machines? Or does the Selfish Gene remain a remarkably powerful and accurate account of who we are?

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